Ottavio Arancio discusses the problematic aspects of therapeutic strategies built upon the amyloid hypothesis of Alzheimer’s disease, and his work defining the synaptic effects of soluble beta amyloid and tau oligomers in the pathogenesis of Alzheimer’s disease.

Duration: 39 minutes

Discussants:(in alphabetical order)

Hyoung-gon Lee (Assoc Prof, UTSA)

Salma Quraishi (Res Asst Prof, UTSA)

George Perry (Semmes Chair, UTSA)

Charles Wilson (Ewing Halsell Chair, UTSA)

acknowledgement: JM Tepper for original music.