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What if your skincare actually reached the layers where change happens? We sit down with Alex, a seasoned aesthetic industry pro, to unpack how Ourself’s biotech roots and TRV tiered release vesicle push big, hard-to-deliver molecules like peptides and hyaluronic acid deeper—10 times deeper than conventional formulas—without needles or harsh enhancers. The result: faster glow, firmer skin, and simpler routines that still outperform crowded vanities.
We trace the founders’ lineage from SkinMedica and Alastin to a new mission focused on delivery science. Alex breaks down the elevator-like TRV system in plain English, explaining why elasticity, collagen, and hyaluronic acid live below the barrier—and why most products never get there. Then we tour the lineup: a gel-to-foam Daily Purifying Cleanser that preps without sting, an HA Replenishing Eye Serum that lifts, brightens, and smooths, and the hero HA Replenishing Serum often dubbed “filler in a bottle” for its multi-active, single-step payoff. We also compare Daily Renewal Cream vs Rich for barrier support and smart hydration across skin types.
Pigment gets the high-science treatment with Complexion Brightening, featuring the new MI9 peptide to block pigment messaging and tranexamic acid delivered deeper than before, alongside vitamin C, niacinamide, and retinol. Expect visible shifts in as little as two weeks without hydroquinone-level irritation. And for a finish that people actually notice, we cover Replenishing Lip Filler 2.0—clinically showing 0.61cc of volume in two weeks—plus the Lip Conditioner that seals moisture for soft, healthy lips without the sting of traditional plumpers.
We also get practical: medical grade versus over the counter, why confocal microscopy and punch biopsies matter, and how the 80-20 rule makes homecare the insurance policy for every facial, laser, or injectable. If you’re ready to streamline your routine and still see real change, this conversation brings the science and the receipts.
Enjoyed the episode? Subscribe, share with a friend who loves skincare, and leave a review to help others find the show.
By Couture Med Spa5
1515 ratings
Send Couture Conversations a text
What if your skincare actually reached the layers where change happens? We sit down with Alex, a seasoned aesthetic industry pro, to unpack how Ourself’s biotech roots and TRV tiered release vesicle push big, hard-to-deliver molecules like peptides and hyaluronic acid deeper—10 times deeper than conventional formulas—without needles or harsh enhancers. The result: faster glow, firmer skin, and simpler routines that still outperform crowded vanities.
We trace the founders’ lineage from SkinMedica and Alastin to a new mission focused on delivery science. Alex breaks down the elevator-like TRV system in plain English, explaining why elasticity, collagen, and hyaluronic acid live below the barrier—and why most products never get there. Then we tour the lineup: a gel-to-foam Daily Purifying Cleanser that preps without sting, an HA Replenishing Eye Serum that lifts, brightens, and smooths, and the hero HA Replenishing Serum often dubbed “filler in a bottle” for its multi-active, single-step payoff. We also compare Daily Renewal Cream vs Rich for barrier support and smart hydration across skin types.
Pigment gets the high-science treatment with Complexion Brightening, featuring the new MI9 peptide to block pigment messaging and tranexamic acid delivered deeper than before, alongside vitamin C, niacinamide, and retinol. Expect visible shifts in as little as two weeks without hydroquinone-level irritation. And for a finish that people actually notice, we cover Replenishing Lip Filler 2.0—clinically showing 0.61cc of volume in two weeks—plus the Lip Conditioner that seals moisture for soft, healthy lips without the sting of traditional plumpers.
We also get practical: medical grade versus over the counter, why confocal microscopy and punch biopsies matter, and how the 80-20 rule makes homecare the insurance policy for every facial, laser, or injectable. If you’re ready to streamline your routine and still see real change, this conversation brings the science and the receipts.
Enjoyed the episode? Subscribe, share with a friend who loves skincare, and leave a review to help others find the show.

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