Episode 73 - Intergalactic BFR with Luke Hughes, PhD

Summary

In this episode, Johnny Owens and Dr. Luke Hughes discuss the applications of Blood Flow Restriction (BFR) in space and its potential to mitigate deconditioning in astronauts. They explore the physiological changes that occur in microgravity, the importance of exercise countermeasures, and the innovative research being conducted to understand the mechanisms behind BFR's effectiveness. The conversation also touches on the implications of BFR for bone health, clinical applications, and future research directions.

Takeaways

BFR is a promising tool for mitigating muscle and bone deconditioning in space.

Fluid shifts in microgravity can lead to significant health issues for astronauts.

BFR can enhance the effectiveness of low-intensity aerobic exercise.

Research is ongoing to understand the mechanisms behind BFR's benefits for bone health.

BFR protocols need to be personalized for different patient populations.

The use of BFR in clinical settings shows potential for improving recovery outcomes.

BFR can help prevent amputations in patients with severe vascular issues.

Understanding the impact of pressure on blood flow is crucial for optimizing BFR protocols.

BFR can be integrated into rehabilitation programs for various conditions.

Future research will focus on the long-term effects of BFR in both space and clinical settings.

Chapters

00:00 Introduction and Overview of Blood Flow Restriction (BFR)

05:38 Bed Rest Studies and Their Importance in Space Research

12:45 Physiological Effects of Microgravity on Astronauts

18:41 Current Exercise Countermeasures in Space Missions

24:04 Future Directions and Innovations in Space Exercise

24:33 Innovations in Exercise Devices for Space Missions

26:41 The Role of Blood Flow Restriction (BFR) in Space Exercise

29:20 First Experiments with BFR in Microgravity

30:37 Collaboration with SpaceX for In-Orbit Research

31:59 Developing Space-Compatible Exercise Devices

33:53 BFR Exercise in Space: A Historic Milestone

35:06 Exercise Protocols and Adjustments for Space Conditions

37:45 Initial Findings from BFR Experiments in Space

40:47 Exploring Fluid Shifts and BFR's Impact

43:33 Combining Aerobic Exercise with BFR for Enhanced Benefits

48:51 Future Directions in BFR Research and Applications

53:07 Exploring Bone Adaptation Mechanisms

55:37 Methodological Framework for Bone Research

59:30 Innovations in Bone Blood Flow Measurement

01:02:31 BFR Applications in Rehabilitation and Pain Management

01:05:17 Future Directions in BFR Research and Space Applications

Podcast Intro Attribution

Song: Legendary

Music by: CreatorMix.com

Video: https://youtu.be/_oaZzkn0bW4

Podcast Outro Attribution

Song: Smoke Rising

Music by: CreatorMix.com

Video: https://youtu.be/_oaZzkn0bW4

This conversation explores the advancements in Blood Flow Restriction (BFR) technology, personal anecdotes related to injury recovery, and insights from recent conferences. The speakers discuss the significance of chronic ankle instability in sports, the effectiveness of BFR in enhancing muscle activation during rehabilitation, and the importance of interdisciplinary collaboration in sports medicine. They also reflect on their experiences and the evolving nature of BFR technology, emphasizing the need for continuous research in this field. This conversation delves into the application of blood flow restriction (BFR) training in rehabilitation, particularly focusing on its effects on muscle activation, balance training, and the challenges faced in research. The speakers discuss various studies, their methodologies, and the implications of using BFR in clinical settings, especially for ankle rehabilitation. They explore the differences between internal and external loads, the importance of programming, and the potential benefits of mobilization techniques combined with BFR. The discussion highlights the need for further research and standardization in BFR protocols to optimize rehabilitation outcomes.

Faltus J, Owens J, Hedt C. THEORETICAL APPLICATIONS OF BLOOD FLOW RESTRICTION TRAINING IN MANAGING CHRONIC ANKLE INSTABILITY IN THE BASKETBALL ATHLETE. doi:10.26603/ijspt20180552

Killinger B, Lauver JD, Donovan L, Goetschius J. The Effects of Blood Flow Restriction on Muscle Activation and Hypoxia in Individuals with Chronic Ankle Instability. J Sport Rehabil. Published online May 16, 2019:1-25. doi:10.1123/jsr.2018-0416

Nagdi MG, Elsayed WH, Abouzied M, Ali RR. Effect of Blood Flow Restriction and Proprioception Training in Recurrent Ankle Sprain Patients. doi:10.33472/AFJBS.6.Si3.2024.10-22

Burkhardt M, Burkholder E, Goetschius J. Effects of blood flow restriction on muscle activation during dynamic balance exercises in individuals with chronic ankle instability. J Sport Rehabil. 2021;30(6):870-875. doi:10.1123/jsr.2020-0334

Clark K, Trickett J, Donovan L, Dawson J, Goetschius J. Effects of Blood Flow Restriction on Balance Performance During Dynamic Balance Exercises in Individuals With Chronic Ankle Instability. J Sport Rehabil. Published online February 13, 2024:1-8. doi:10.1123/jsr.2023-0182

Werasirirat P, Yimlamai T. Effect of supervised rehabilitation combined with blood flow restriction training in athletes with chronic ankle instability: a randomized placebo-controlled trial. Eur J Cardiovasc Prev Rehabil. 2022;18(2):123-132. doi:10.12965/jer.2244018.009

Kim H, Jung J, Lee S. Contributory effect of additional blood flow restriction in active joint mobilization for young adults with chronic ankle instability: A pilot randomized controlled trial. Phys Ther Rehabil Sci. 2023;12(4):486-492. doi:10.14474/ptrs.2023.12.4.486

Summary

In this episode of the Owens Recovery Science podcast, hosts Kyle Kimbrell and Zac Dunkle discuss the significance of Memorial Day, and share humorous military anecdotes. They emphasize the importance of supporting veterans and Gold Star families, highlighting various foundations that provide assistance and resources for those in need. The conversation blends humor with serious reflections on sacrifice, mental health, and community support.

Chapters

00:00 Introduction and Podcast Changes

02:18 Memorial Day Reflections

18:01 Understanding Memorial Day's Significance

23:13 Zac's Military Journey

25:27 The Influence of Movies on Career Choices

27:04 Education and Military Experience

29:49 The Rigors of Sniper School

33:05 Mindset and Test Anxiety

34:49 Honoring Fallen Comrades

39:22 Mental Health and Support for Veterans

40:57 Understanding the Multifactorial Nature of Veteran Suicide

44:45 Finding Purpose After Service

50:18 Foundations Supporting Veterans and Their Families

56:54 Unit-Specific Foundations and Their Impact

01:05:06 Connecting with Resources and Support

01:06:38 Taps_Matt_Harding.mp3

Foundations we mentioned:

https://www.warriorsandquietwaters.org/

https://www.reconfoundation.org/

https://www.reconsniperfoundation.org/

https://www.kuiu.com/

https://www.sitkagear.com/

https://www.allsecurefoundation.org/

https://headwatersforheroes.com/

Episode 70 - On this episode of the ORS Podcast we welcome Yujiro Yamada. Yuji is a Ph.D. candidate in the Department of Health, Exercise Science, and Recreation Management at the University of Mississippi. He is a member of the Kevser Ermin Applied Physiology Lab, working under the supervision of Dr. Jeremy P. Loenneke. Yujiro earned his bachelor's degree in exercise science from Ohio Dominican University (Columbus, OH) and his master's in exercise science from the University of Mississippi (Oxford, MS). His research focuses on the physiological responses to resistance exercise, with and without blood flow restriction, and its impact on muscle and cognitive adaptations.

Alex Smith piece on ESPN: https://www.espn.com/video/clip/_/id/42306520

Shaw Strength Podcast: https://www.youtube.com/watch?v=5wrgQA8VU0c

Chief paper discussed:

Yamada, Yujiro; Hammert, William; Kataoka, Ryo; Song, Jun Seob; Kang, Anna; Kassiano, Witalo; Loenneke, Jeremy; The role of the muscle metaboreflex on cardiovascular responses to submaximal resistance exercise with different pressures and modes of blood flow restriction. Applied Physiology, Nutrition, and Metal. 2024.

We answer a listener question about how to manage a limb that is non-weightbearing for a period of time.

Kyle goes on an epic rant about what we can and can't do to care for our patients / clients.

Chief paper discussed:

T Parkington, T Maden-Wilkinson, D Broom, S Nawaz... (2023). Low-Intensity Resistance Exercise with Blood Flow Restriction for Patients with Claudication: A Randomised Controlled Feasibility Trial. Vascular Medicine .

Position statement on managing PAD:

Askew, C. D., Parmenter, B., Leicht, A. S., Walker, P. J., & Golledge, J. (2014). Exercise & Sports Science Australia (ESSA) position statement on exercise prescription for patients with peripheral arterial disease and intermittent claudication. Journal of Science and Medicine in Sport / Sports Medicine Australia, 17(6), 623–629.

Additional papers referenced:

Bentzen, A., Nisgaard, L. B., Mikkelsen, R. B. L., Høgh, A., Mechlenburg, I., & Jørgensen, S. L. (2023). Blood flow restricted walking in patients suffering from intermittent claudication: a case series feasibility and safety study. Annals of Medicine and Surgery (2012), 85(5), 1430–1435.

Saes, G. F., Zerati, A. E., Wolosker, N., Ragazzo, L., Rosoky, R. M. A., Ritti-Dias, R. M., Cucato, G. G., Chehuen, M., Farah, B. Q., & Puech-Leão, P. (2013). Remote ischemic preconditioning in patients with intermittent claudication. Clinics , 68(4), 495–499.

Ahmed, K. M., Hernon, S., Mohamed, S., Tubassum, M., Newell, M., & Walsh, S. R. (2018). Remote ischemic preconditioning in the management of intermittent claudication: a pilot randomized controlled trial. Annals of Vascular Surgery. https://doi.org/10.1016/j.avsg.2018.07.046

Podcast w/ Jamie Burr we referenced:

https://owensrecoveryscience.com/podcasts/owens-recovery-science-podcast-bfr-ipc-for-performance-rehab-and-health-w-jamie-burr-phd

In this episode of the ORS podcast Johnny and Kyle discuss all things PT and career trajectory as well as managing knee cartilage repairs with Snay Patel, PT. Snay is a PT at HSS and has an extensive background in the rehab of people following knee cartilage procedures. Let us know what you think of the pod an who we should have on next!

In this episode of the Owens Recovery Science podcast, Johnny and Kyle interview Annie Bane, PhD regarding her research into people with Parkinson’s Disease and the use of Blood Flow Restriction Resistance Exercise as a maintenance strategy. Dr. Bane is a wealth of knowledge on how treatment strategies and the disease progression of PD affect the cardiovascular system. This was ultimately the target of her dissertation research while at Baylor and her findings are very exciting. We know you will enjoy this chat!

If you know someone in the Abilene area that could benefit from the exercise program for people with Parkinson’s please have them email Jill Jumper, PT, PhD at [email protected]

If you would like to see Dr. Bane's TV show on she and her husband's gym in Abilene, TX the show is called "The Fieldhouse". It aired on the Magnolia Network and can now be found on Amazon Prime too.

Dr. Bane’s paper:

Bane, A., Wilson, L., Jumper, J., Spindler, L., Wyatt, P., & Willoughby, D. (2024). Effects of blood flow restriction resistance training on autonomic and endothelial function in persons with Parkinson’s disease. Journal of Parkinson’s Disease, 1–15.

The Hong paper referenced:

Hong, C. T., Hu, H.-H., Chan, L., & Bai, C.-H. (2018). Prevalent cerebrovascular and cardiovascular disease in people with Parkinson’s disease: a meta-analysis. Clinical Epidemiology, 10, 1147–1154.

If you jump in your wayback machine you can find our first episode with our distinguished guest on this installment of the Owens Recovery Science Podcast! And just like the first time she did not disappoint! Sherry Johnson, DVM, PhD, DACVSMR is a sports medicine physician for equine athletes. That's right y'all! Literal horses. She co-owns a private practice specializing in the care of very elite athletic horses that run the gamut event types with locations in Texas and Arizona. In her spare time!! She does BFR research. Well I'm tired just from typing that! Hope y'all enjoy our chat. Below are two of her BFR papers on horses.

Johnson SA, Chicco AJ, Selberg KT, King MR, Dunkle ZP, Owens JG, Frisbie DD. Short-term effects of blood flow restriction training on equine skeletal muscle oxidative capacity. In: Orthop Res Soc Annual Meeting, Poster Presentation, 12–16. February 2021.

Johnson, S. A., Frisbie, D. D., Griffenhagen, G. M., & King, M. R. (2022). Equine blood flow restriction training: Safety validation. Equine Veterinary Journal. https://doi.org/10.1111/evj.13904

In episode 65 Johnny makes his triumphant return after defeating Montezuma’s revenge to help the guys breakdown a couple recent publications on BFR and rehab after ACLr. Zac takes the lead on the first of the papers that had a bit of a clickbait title per the fellas assessment. The paper titled, “‘Real world’ clinical implementation of blood flow restriction therapy does not increase quadriceps strength after quadriceps tendon autograft ACL reconstruction” has a number of demographic problems the fellas discuss, and ultimately evaluated one of the least relevant outcome measures by their estimation. Kyle finishes up the breakdown with some alternate and far more accurate title suggestions for the paper.

The second paper they discuss was a recent review paper on ACL and BFR. Ben takes the lead breaking down this paper where the fellas have a tough time sorting why some studies were excluded and why at least one was included. Long story short the evidence on BFR use in ACLr rehab is still very limited and a review focusing on most all aspects of that process should be read with a healthy level of skepticism.

Find us at:

June 26-27: https://convention.nata.org/

June 29-30: https://hockey.eliterehabconferences.com/

July 13-14: https://basketball.eliterehabconferences.com/

Medbridge ACL Series: https://www.medbridge.com/