DuQuette has written several successful books on Western mystical traditions including; Freemasonry, Tarot, Qabalah, ceremonial magic, the Enochian magic of Dr. John Dee, and spirit evocation, Goetia. He is perhaps best known for his autobiography, My Life with the Spirits, which is currently a required text for two classes at DePaul University, Chicago.

Many of DuQuette's books have been dedicated to analyzing and exploring the works of Aleister Crowley (1875–1947), an English occultist, author, poet and philosopher.

DuQuette occasionally appears on radio and television as a guest expert on subjects involving the occult.

He is on the faculty of the Omega Institute for Holistic Studies in Rhinebeck, New York where he teaches The Western Magical Tradition.