Episode 352 is Pan Am (2011)

"Pilot"

Dean takes on his first assignment since his promotion, piloting the Clipper Majestic on its inaugural New York to London flight. Bridget is supposed to be his lead stewardess, until she's a no-show for the flight. Grounded purser Maggie is called in to fill in for her. On the same fateful flight, Kate adds another dimension to her work as she takes on her first assignment from U.S. intelligence. Her stress is compounded when she discovers that newly minted stewardess, Laura, her sister, is also working the same flight.