The standard advice (taught to paediatric trainees and written on handouts to parents) is that paracetamol does not reduce the recurrence rate of subsequent febrile seizures. (However, even the 2017 Cochrane review on prophylaxis for febrile seizures is largely silent about paracetamol – it focuses mainly on anticonvulsants). This recent study from Japan challenges what we thought we knew.

 

Paediatrics, October 2018