Please visit answersincme.com/TDH860 to participate, download slides and supporting materials, complete the post test, and obtain credit. In this activity, an expert in metabolic diseases discusses metachromatic leukodystrophy (MLD). Upon completion of this activity, participants should be better able to: Explain the clinical burden and unmet needs in MLD; Describe the signs and symptoms of MLD to facilitate early diagnosis and intervention; and Outline potential strategies to optimize outcomes for patients with MLD.