This episode is about Paxlovid (nirmatrelvir and ritonavir) - the recently approved at-home oral COVID 19 treatment for those with mild to moderate symptoms and at risk of progression to severe COVID 19. In this episode, I discuss who would benefit from this medication, conditions where it should not be used or prescribed, examples of drug interactions, side effects of the medication and some of the data points from the original Pfizer trial that evaluated the use of this drug.