In preterm neonates with a patent ductus arteriosus (PDA), the standard of care has been to attempt to close the defect. Yet some experts have asked whether we need to treat PDA in most preemies. If we are to resolve the condition, there are various methods and protocols for treatment and even prevention; how do outcomes for PDA closure vary by treatment strategy? Dr. Darshak Sanghavi, chief of pediatric cardiology and assistant professor of pediatrics at the University of Massachusetts Medical School, lays out the important points of discussion on PDA closure with host Dr. Jennifer Shu.