MIC: More Infection Chat

Persistent candidaemia, why does it happen; and a new Meningoencephalitis reference guide


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In this episode we discuss a study looking at persistent candidaemia (based on the Candida III study), as well a new quick reference guide on Meningoencephalitis.

The Candida III sub-analysis study can be accessed here
https://www.journalofinfection.com/article/S0163-4453(25)00229-4/fulltext

Read more about Candida IV here
https://www.ecmm.info/working-groups/2219/

The IQRG meningitis/encephalitis article is here
https://www.sciencedirect.com/science/article/pii/S2590170225001190

A higher resolution copy here
https://www.britishinfection.org/application/files/1117/3615/0506/Investigation_of_Meningitis_and_Encephalitis.pdf

And other IQRGs can be accessed on the BIA’s website
https://www.britishinfection.org/guidance/published-guidelines

UK SMI B27 for investigation of CSF
https://www.rcpath.org/static/004f2dc9-81cb-4aa9-b26f2dfce68a9921/UK-SMI-B-27i62-Investigation-of-cerebrospinal-fluid-October-2025.pdf

Cochrane meta-analysis for steroids is here
https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD004405.pub5/full

And Dr Fiona McGill's previous guidelines on meningitis from 2016 is here
https://www.journalofinfection.com/article/S0163-4453(16)00024-4/fulltext

And the UK 2017 audit of the guidelines mentioned is worth a read here
https://bmjopen.bmj.com/content/12/7/e062698

Plus the DexEnceph study of steroids in HSV Encephalitis is on the Lancet website 
https://www.thelancet.com/journals/laneur/article/PIIS1474-4422(25)00454-5/fulltext

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MIC: More Infection ChatBy British Infection Association