We're heading into Week 5 of the NFL regular season! Simms and Lefkoe are here to pick every game on the NFL slate against the spread. Chris and Adam tell you how to bet all of the games: Cardinals-Eagles (8:05); Bills-Bengals (11:50); Panthers-Lions (15:00); Steelers-Jaguars (17:45); Jets-Browns (23:15); Chargers-Giants (27:40); Titans-Dolphins (31:05); 49ers-Colts (31:50); Ravens-Raiders (33:20); Seahawks-Rams (34:15); Packers-Cowboys (38:20); Chiefs-Texans (41:40); and Vikings-Bears (45:45). Of course, Simms also picks his 5 Teams Guaranteed to Lose to close out the show (49:37). Let us know what you think of our picks on Twitter @SimmsAndLefkoe and don't forget to leave us a 5-star review on iTunes!See omnystudio.com/listener for privacy information.

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