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In Episode 2 of Inpatient Update, your host, Dr. Mason Turner, breaks down three studies that could change what you do on rounds tomorrow:

• Phenobarbital for alcohol withdrawal — fewer admissions and shorter ED stays during the IV lorazepam shortage natural experiment.
• Conservative dialysis in AKI requiring RRT (LIBERATE-D) — less routine dialysis, more kidney recovery?
• Postoperative transfusion thresholds in high–cardiac-risk patients (TOP Trial) — is 7 still enough?

Articles & PubMed Links

1. Fewer Admissions, Shorter Stays: Phenobarbital Use for Alcohol Withdrawal in the Emergency Department
   Academic Emergency Medicine (2025)
   PubMed: https://pubmed.ncbi.nlm.nih.gov/41147831/
2. A Conservative Dialysis Strategy and Kidney Function Recovery in Dialysis-Requiring Acute Kidney Injury (LIBERATE-D Trial)
   JAMA ( 2026)
   PubMed: https://pubmed.ncbi.nlm.nih.gov/41201895/
3. Liberal or Restrictive Postoperative Transfusion in Patients at High Cardiac Risk: The TOP Randomized Clinical Trial
   JAMA (2025)
   PubMed: https://pubmed.ncbi.nlm.nih.gov/41205227/

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