In this episode, Prof Chapman tackles one of the most heartbreaking questions in fertility, why miscarriages keep happening. Responding to a listener who has faced four losses across natural and IVF conceptions, he walks through the biggest culprit, genetic abnormalities in the embryo, and explains why age and egg quality sit at the centre of it all. He unpacks the other hidden causes worth investigating, from chromosome translocations carried by healthy parents to fibroids, scar tissue, and abnormalities in the shape of the womb. Along the way he covers the surprising fertility effects of COVID, the global decline in birth rates, and why more women in their early 30s are choosing to freeze their eggs while quality is still on their side. Practical, honest, and deeply reassuring for anyone navigating the road to a baby.

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In this episode, Prof Chapman unpacks what specialists actually mean when they talk about egg quality. He explains that quality comes down to an egg’s competency to fertilise and produce an embryo with the right number of chromosomes, and why that process becomes less reliable as women age. He describes the tiny energy-producing structures called mitochondria, the batteries inside every egg, and how their decline disrupts the delicate work of lining up chromosomes at the right moment. He also walks through the spindle, the internal structure his own team studies using polarised light at Life Fertility, and how checking it before fertilisation helps predict whether a pregnancy is likely. It is an honest, reassuring look at the uphill odds women over 40 face, why most early miscarriages trace back to the egg rather than the parents, and what the science can and cannot tell us.

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In this episode, Prof Chapman explains one of fertility’s biggest puzzles: why a woman’s biological clock runs down so much faster than the rest of her body. Drawing on decades of experience and more than three and a half thousand babies, he walks through the remarkable journey of your eggs, from the millions laid down before you were even born, to the half a million you had at birth, to the slow decline that ends in menopause. He unpacks why older women get fewer eggs from IVF, what the AMH test can and can’t tell you, and the crucial difference between egg quantity and egg quality. A clear, honest look at the science every woman deserves to understand.

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In this episode, Prof Chapman and fertility nurse Natalie tackle one of the most-asked questions on the YouTube channel: the recent renaming of PCOS to PMOS. Prof Chapman explains how the change came out of a roomful of specialists, each with their own stake in the name, and why he sees it as a positive move, not least because so many patients hear “cysts on the ovary” and immediately worry about cancer. He unpacks what the new name signals about the hormonal and metabolic sides of the condition, while making clear that the condition itself hasn’t changed at all. And above everything else, he keeps the focus where it matters most for the women he sees: getting pregnant.

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In this episode, Prof Chapman is joined by fertility nurse Natalie to answer one of the most common questions from listeners: what should you do when you’re in your 40s and cycle after cycle isn’t working? Natalie explains why going back to basics matters — reviewing your initial workup, checking whether tests like AMH and antral follicle counts need repeating, and looking at inflammatory markers that may be overlooked. She walks through what a thorough second opinion involves, from treatment protocols and medication dosages to egg numbers, insemination methods and blastocyst outcomes, and why genetic testing (PGT-A) is often never discussed despite being valuable. If you’re wondering whether to push on or pause and reassess, this episode is for you.

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In this episode, Prof Chapman answers a listener question about the future of IVF, covering what innovations are genuinely exciting and whether treatment will become more accessible and affordable. He reflects on how success rates have climbed from 10% to around 40% per embryo transfer over three decades, and gives his honest take on the current “flavours of the month”: AI in embryo selection, non-invasive genetic testing, and research into environmental toxins. With a fertility nurse adding the patient perspective on accessibility and public sector options, this is a candid look at where fertility science is really heading, and why steady 1% gains may matter more than headline breakthroughs.

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Don’t miss out on the IVF Journey podcast; stay informed with the latest episode updates. Tune in for expert discussions and valuable information on navigating the intricate path of IVF.

In this episode, Prof Chapman sits down with fertility nurse Natalie to talk about the moments IVF patients often face alone — the late-night bleeding scare, the anxious wait after a positive test, the questions that come up between appointments. They discuss why a positive pregnancy test isn’t the finish line, the reassurance of regular early-pregnancy monitoring through to 10 weeks, and how fertility care is shifting towards truly patient-centred support, where feeling informed, heard and supported matters just as much as clinical outcomes.

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Don’t miss out on the IVF Journey podcast; stay informed with the latest episode updates. Tune in for expert discussions and valuable information on navigating the intricate path of IVF.

In this episode, Prof Chapman is joined by a fertility nurse to unpack what should happen after a failed IVF cycle — and why so many patients are left without answers. They explore the emotional fallout of a negative pregnancy test, the delays patients face in getting support from busy clinics, and the value of having someone who can genuinely listen between appointments. Prof Chapman also shares his frustration with clinics that simply repeat the same protocol after a failed cycle, explaining why a detailed review of drug dosages, egg numbers, and fertilisation outcomes is essential before planning the next attempt — plus when it might be time to seek a second opinion.

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Don’t miss out on the IVF Journey podcast; stay informed with the latest episode updates. Tune in for expert discussions and valuable information on navigating the intricate path of IVF.

In this episode, Prof Chapman is joined by a fertility support nurse to explore the gaps in patient care during IVF treatment. They discuss the most common concerns women face — from needle phobia and administering that first injection, to post-egg-collection bleeding and knowing when symptoms warrant escalation. Prof Chapman offers a frank comparison of Australia’s premium versus low-cost IVF clinics, and why patients often absorb only a fraction of what they’re told in consultations — leaving many too embarrassed to ring their clinic with “silly” questions that deserve real answers.

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Don’t miss out on the IVF Journey podcast; stay informed with the latest episode updates. Tune in for expert discussions and valuable information on navigating the intricate path of IVF.

Prof. Chapman introduces Natalie from Australia IVF Concierge, highlighting the emotional and practical support gap patients face at home during fertility treatment. Focus: the psychological burden of IVF (60% first-cycle failure rate), medication management, injection anxiety, and waiting uncertainty. Natalie explains how nurse-led home visits provide reassurance, education, and holistic support beyond clinic appointments—positioning aftercare as essential to the patient journey.

Explore the ‘Prof. Michael Chapman – The IVF Journey’ Facebook Page, your reliable destination for cutting-edge insights and guidance within

Don’t miss out on the IVF Journey podcast; stay informed with the latest episode updates. Tune in for expert discussions and valuable information on navigating the intricate path of IVF.