PCP Lens Podcast

Podcast - What is a Disease?


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DescriptionWhat exactly is a disease, and how do we decide where normal ends and illness begins?

In this thought-provoking exploration, I break down the complex "biologic pathway" of disease to highlight how definitions evolve over time. From the role of biomarkers and "pre-disease" categories to the influence of pharmaceutical companies on diagnostic thresholds, this video dives into the scientific, social, and economic factors shaping modern medicine. Discover how redefining diseases impacts healthcare, overdiagnosis, and even public perception—raising critical questions about what it truly means to be "sick."

Chapter Markers

- 00:00 - Intro

- 01:08 - The Biologic Pathway of Disease

- 03:46 - Goals of Defining a Disease

- 04:20 - Defining a Disease

- 07:54 - What is Normal?

- 09:55 - Evolution of Disease Definitions

- 12:37 - At the Intersection of Doubts, Decisions and Dollars

- 15:20 - Outro

Link to Written Article: https://www.pcplens.com/p/what-is-a-disease

Link to Video: https://www.pcplens.com/p/podcast-what-is-a-disease

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PCP Lens PodcastBy Medicine + Metrics + Money + Madness = Healthcare