Infant Vitamin D requirements of 400 IU are only being met a fraction of the time, as compliance postpartum remains an issue with this busy and challenging phase of life. 

In this podcast, we discuss the most recent systematic review by Coresello (2022) discussing various Vitamin D supplementation strategies postpartum, and potential alternatives to infant dosing strategies. We take a deep dive into two of the studies discussed that provide different maternal Vitamin D dosing strategies, one that includes daily dosing (Hollis 2015) and the other that utilizes monthly dosing (Chandy 2016). We also discuss the Cochrane Review on this topic (Tan 2020) which covers their review of Vitamin D dosing in exclusively breastfed infants. 

 

References: 

Chandy, D. D., Kare, J., Singh, S. N., Agarwal, A., Das, V., Singh, U., Ramesh, V., & Bhatia, V. (2016). Effect of vitamin D supplementation, directly or via breast milk for term infants, on serum 25 hydroxyvitamin D and related biochemistry, and propensity to infection: A randomised placebo-controlled trial. The British Journal of Nutrition, 116(1), 52–58. https://doi.org/10.1017/S0007114516001756

 

Corsello, A., Milani, G. P., Giannì, M. L., Dipasquale, V., Romano, C., & Agostoni, C. (2022). Different Vitamin D Supplementation Strategies in the First Years of Life: A Systematic Review. Healthcare (Basel, Switzerland), 10(6), 1023. https://doi.org/10.3390/healthcare10061023

 

Hollis, B. W., Wagner, C. L., Howard, C. R., Ebeling, M., Shary, J. R., Smith, P. G., Taylor, S. N., Morella, K., Lawrence, R. A., & Hulsey, T. C. (2015). Maternal Versus Infant Vitamin D Supplementation During Lactation: A Randomized Controlled Trial. Pediatrics, 136(4), 625–634. https://doi.org/10.1542/peds.2015-1669

Tan, M. L., Abrams, S. A., & Osborn, D. A. (2020). Vitamin D supplementation for term breastfed infants to prevent vitamin D deficiency and improve bone health. The Cochrane Database of Systematic Reviews, 12(12), CD013046. https://doi.org/10.1002/14651858.CD013046.pub2