Missions Conference 2025 - Jeff Johnson The sermon centers on the indispensable role of prayer in sustaining missionary work, emphasizing that while financial support is essential, prayer is the most powerful and transformative spiritual resource. Drawing from 2 Thessalonians 3:1, it highlights how consistent, heartfelt prayer empowers missionaries through cultural shock, language barriers, emotional isolation, and even life-threatening dangers, providing comfort and strength when material resources fail. The speaker illustrates these truths with personal stories of miscommunication, hardship, and divine provision, underscoring that every missionary faces unseen struggles that only prayer can alleviate. He calls the church to move beyond passive support by making a deliberate, daily commitment to prayer—adding even a few minutes each day—as a vital act of spiritual partnership that fuels global mission. Ultimately, the message affirms that prayer is not a secondary concern but the foundational force behind every breakthrough, revival, and enduring faith in the mission field.