In Isaiah 6, we witness a powerful divine encounter that reveals what happens when God shows up. During a time of national uncertainty following King Uzziah's death, Isaiah sees God on His throne surrounded by seraphim declaring His holiness. This vision exposes Isaiah's sinfulness in contrast to God's perfect holiness, leading to his confession and God's gracious cleansing. After being purified, Isaiah hears God's call and responds without hesitation: Here am I. Send me. This passage teaches us that when we encounter God's holiness, we see ourselves clearly, receive His grace, and are called to respond with complete availability to His purposes.