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Phototherapy: UVB 290-320, UVA 320-400, can be used to treat skin diseases, such as psoriasis, can cause burns, cancer, and aging
Potassium hydroxide (KOH) mount: can diagnose dermatophyte infection via scraping of the edge of a scaling lesion and placing a drop or two of KOH w dimethylsulfoxide (DMSO) on the slide, blot, examine w low illumination, low power, looking for hyphae, can be difficult to find, can also use to diagnose candidal infection if you see hyphae/pseudohyphae
Tzanck: can diagnose herpetic infection via scrapings from vesicular lesions, can see multinucleated giant cells, for herpetic viral infections can also do immunofluorescent staining
Scabies: can do a scraping of a suspected burrow and visualize the mite
Cultures: scrapings, swabs, biopsies can be sent to assess for bacterial, viral, or fungal growth
Biopsy: punch, shave
Patch tests: used in diagnosing allergic contact dermatitis, patches left on the skin for 2 days
Immunofluorescence: can detect autoantibodies to diagnose blistering disorders
Mohs micrographic surgery: used for basal and squamous cell carcinomas of the skin, layers are removed and examined one at a time to ensure all of the margins of a tumor are removed
Excision: gets tissue sample for study, can remove lesions, length 3x the width, use sutures to close
Electrodessication and curettage: for removal of carcinomas, remove w curette and tx w electrode to destroy remaining cancerous cells
Cryosurgery: uses super cold liquid nitrogen, often used to tx warts or other common lesions such as seborrheic keratoses
With all surgeries and invasive procedures, make sure to get informed consent, discuss complications (neural damage, scarring, infection), discuss alternatives, and educate your patient on their condition!
References: AAD Basic Dermatology Curriculum, Dermatology by Bolognia et. al., Lookingbill and Mark's Principles of Dermatology, First Aid USMLE Step 1 2020, First Aid USMLE Step 2 CK
By Zachary LoweryPhototherapy: UVB 290-320, UVA 320-400, can be used to treat skin diseases, such as psoriasis, can cause burns, cancer, and aging
Potassium hydroxide (KOH) mount: can diagnose dermatophyte infection via scraping of the edge of a scaling lesion and placing a drop or two of KOH w dimethylsulfoxide (DMSO) on the slide, blot, examine w low illumination, low power, looking for hyphae, can be difficult to find, can also use to diagnose candidal infection if you see hyphae/pseudohyphae
Tzanck: can diagnose herpetic infection via scrapings from vesicular lesions, can see multinucleated giant cells, for herpetic viral infections can also do immunofluorescent staining
Scabies: can do a scraping of a suspected burrow and visualize the mite
Cultures: scrapings, swabs, biopsies can be sent to assess for bacterial, viral, or fungal growth
Biopsy: punch, shave
Patch tests: used in diagnosing allergic contact dermatitis, patches left on the skin for 2 days
Immunofluorescence: can detect autoantibodies to diagnose blistering disorders
Mohs micrographic surgery: used for basal and squamous cell carcinomas of the skin, layers are removed and examined one at a time to ensure all of the margins of a tumor are removed
Excision: gets tissue sample for study, can remove lesions, length 3x the width, use sutures to close
Electrodessication and curettage: for removal of carcinomas, remove w curette and tx w electrode to destroy remaining cancerous cells
Cryosurgery: uses super cold liquid nitrogen, often used to tx warts or other common lesions such as seborrheic keratoses
With all surgeries and invasive procedures, make sure to get informed consent, discuss complications (neural damage, scarring, infection), discuss alternatives, and educate your patient on their condition!
References: AAD Basic Dermatology Curriculum, Dermatology by Bolognia et. al., Lookingbill and Mark's Principles of Dermatology, First Aid USMLE Step 1 2020, First Aid USMLE Step 2 CK