Professor David Nutt, voted by The Times as one of the hundred most important figures in British science and Chair of the Independent Scientific Committee on Drugs, and President of the British Neuroscience Association, whose advisory role in Tony Blair's government came to a sudden end over his analysis that horse riding was more dangerous than ecstasy. Famed for forcing a fact based debate around drugs onto the agenda, Professor Nutt explains the importance of understanding the role pleasure plays when examining our relationship with drugs.