This release contains only the music track from Base by Base Episode 18.

Song title: Quality Control Hearts
Original Base by Base episode: 18: UGGT1-CDG: Bi-allelic UGGT1 variants and a new congenital disorder of glycosylation

Article metadata:
Article title: Bi-allelic UGGT1 variants cause a congenital disorder of glycosylation
Journal: The American Journal of Human Genetics
DOI: 10.1016/j.ajhg.2025.03.018
Reference: Dardas Z., Harrold L., Calame D.G., et al. Bi-allelic UGGT1 variants cause a congenital disorder of glycosylation. The American Journal of Human Genetics. 2025;112:1139–1157. https://doi.org/10.1016/j.ajhg.2025.03.018

Lyrics:
Verse 1
In the quiet of a cell-lit room,
A careful gate was built to face the gloom,
Tag the wrong folds, send them back in line,
Keep the fragile proteins doing fine.

Pre-Chorus
But two small breaks can rewrite the plan,
A missing stitch, a slipping hand,
A signal lost at the ER door,
And what was kept spills to the floor.

Chorus
Hold on—shine that sugar light,
Guide the shape back through the night,
When the folding fails and the warnings start,
We’re still learning “why” by heart.
Quality control hearts—don’t let go,
Name the glitch so care can grow.

Verse 2
Some kids carry storms behind their eyes,
Seizures like sparks in the midnight skies,
Small head, big fight, days that feel too steep,
And tests look calm while the secrets keep.

Bridge
Not every loss shows up in a standard screen,
So read the code where the truth has been,
From gene to function, trace the thread,
To tell what’s coming—softly said.

Final Chorus
Hold on—shine that sugar light,
Guide the shape back through the night,
If the enzyme’s gone or the message bends,
We can still map where the damage ends.
Quality control hearts—stand tall,
Sequence the answer when markers stall,
And from the fold, a clearer start:
We’re turning cause into care—by heart.