Welcome to the Quantum News Daily Brief. Story 1: COMET: Combinatorial Optimization for Multiplex Editing Targets Via Constraint-Preserving QAOA. A team led by Priyansh Singhal, Sumit Maheshwari, and Piyush Joshi introduced COMET, a method comparing constraint-enforcement strategies for multiplex CRISPR-Cas9 gene editing using QAOA. Their study targets immune-checkpoint genes PDCD1, LAG3, and HAVCR2 on a twelve-qubit system. In simulations, the XY-mixer approach achieved over 95% probability of