https://www.ploquickpro.com/quickfact-10-kk-flops-top-set-80-85-of-the-time-qq-flops-top-set-65-70-of-the-time

Alongside suitedness and connectedness, high card strength is the other determining characteristic of any starting hand. If you ever get the chance to look through a successful PLO player's database, the first thing to notice is how their most profitable starting hands are big cards. This is not a coincidence; big cards intrinsically possess more post-flop equity on average than little cards do.

Holding overcards on low boards illustrates this concept. To explain a bit further, let's use a Hold'em analogy. When check-raising a T♣6♦2♥ board in NLHE, we would much rather have A♣Q♣ than a hand like 5♥5♦, because when someone decides to look us up with a pair, our equity is greater holding the live overcards and backdoor equity than with just the pocket pair. You can think about overcards the same way in PLO.

http://www.youtube.com/watch?v=xU1JVoDgsUg

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Pot Limit Omaha Strategy + Winning PLO Strategy Guide