The fifth episode of the rebooted After Office Hours features discussions on healthcare. The first by Simon Ocampo on race, ethnicity, and medical mistrust, and the second is by Quinn Kinney on trans substance users’ challenges navigating healthcare. Featuring interviews with Professors Jay Pearson, Sanjiv Gupta, and Shanna K. Kattari, our two hosts ask important questions about how to improve the lives and health outcomes of a diverse array of people.