Primatologist Davis Okoye shares an unshakable bond with George, an extraordinarily intelligent, silverback gorilla that's been in his care since birth. When a rogue genetic experiment goes wrong, it causes George, a wolf and a reptile to grow to a monstrous size. As the mutated beasts embark on a path of destruction, Okoye teams up with a discredited genetic engineer and the military to secure an antidote and prevent a global catastrophe.

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