REBEL Cast Ep 118: The PROCOAG Trial – 4F-PCC for Trauma Patients?

Background: Hemorrhage is the leading cause of mortality in trauma patients.  Interventions such as early application of hemorrhage control, tranexamic acid, reduction of crystalloid  fluid administration and balanced ratio blood product transfusion have improved many patients’ outcomes. However, mortality still remains high due to trauma-induced coagulopathy. Some clinicians have advocated for early administration of 4-factor ... Read more