Take Home Points Adrenal insufficiency is a life-threatening emergency; recognize early and treat aggressively Hallmark is hypotension refractory to IVF/pressors Suspect in patients with unexplained hypotension and risk factors Prior glucocorticoid therapy History of autoimmune diseases Hyperpigmentation  AIDS or TB history Treat empirically with hydrocortisone 100mg IV and search for precipitating causes Less than 50% ... Read more