We discuss a new research publication on cannabis hyperemesis from Dr. Ethan Russo and Nishi Whiteley, and a review article on serotonin receptors & psychedelics. This episode also offers the opportunity to learn the answers to important questions like, what are the potential risks and benefits of naturalistic mescaline use and what are non-psychedelic psychedelics? We also discuss indigenous populations and maple syrup. The show ends with a new game, Name that Drug! - Dr. Marcu reads a case report about an experimental drug treatment, while guests try to figure out if it was THC, psilocybin, LSD or a CBD extract.