PaperPlayer biorxiv bioinformatics

Recovering genomes and phenotypes using allele-specific gene expression


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Link to bioRxiv paper:
http://biorxiv.org/cgi/content/short/2020.11.11.377978v1?rss=1
Authors: Gursoy, G., Lu, N., Wagner, S., Gerstein, M.
Abstract:
With the recent increase in RNA sequencing efforts using large cohorts of individuals, studying allele-specific gene expression is becoming increasingly important. Here, we report that, despite not containing explicit variant information, a list of allele-specific gene names of an individual is enough to recover key variants and link the individual back to their genome or phenotype. This creates a privacy conundrum.
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