In this episode, we review the physiology and pathophysiology, etiology, clinical exam, investigations and treatment in patients with splenomegaly. Our medicine minute addresses the COMFORT II trial published in the New England Journal of Medicine in 2012. 

Written by: Drs. Owen Luo and Jia Li (Lily) Liu (Internal medicine residents)
Reviewed by: Dr. Gizelle Popradi (hematologist) and Dr. Samuel Mamane (general internist)  Support the Show.

221. Red Pulp, White Pulp - An approach to splenomegaly

A pan-Canadian learner-generated internal medicine podcast. The Intern at Work is written by residents for residents, and is meant to serve you better on the wards and on call. Disclaimer: This podcast is intended for educational use only and is not intended as the sole resource for clinical management. All scripts are original scripts. Podcasts produced out of Canada and may contain Canadian specific guidelines. Created by: Alison Lai Executive Producers: Laiya Carayannopoulos, Zahra Merali

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Written by: Dr. Lori Israelian (Internal Medicine Resident) 
Reviewed by: Dr. Eva Piessens (Infectious Diseases) & Dr. Jessica Huynh (General Internal Medicine)  Support the Show.

235. Galloping Gangrene - An Approach to Necrotizing Fasciitis

In this episode, we discuss the pathophysiology, clinical manifestations and treatment of familial mediterranean fever (FMF). Our medicine minute discusses the history of colchicine use in FMF. 

Written by: Dr. Sara Choi (Internal Medicine Resident)
Reviewed by: Dr. Zijing Wu (General Internist) and Dr. Marie Clements-Baker (Rheumatologist)
Sound editing by: Tony Walsh Support the Show.

234. Stop the Attacks - An Approach to Familial Mediterranean Fever

You may know an approach to anemia, or thrombocytopenia...but what about when all cell lines are down? Take a listen to our hematology focused episode of pancytopenia!
Written by Jia Li (Lily) Liu (Internal Medicine Resident) and Dr. Owen Dan Luo (Internal Medicine Resident) and reviewed by Dr. Laura Habib (Hematologist-Oncologist), and Dr. Natasha Nathoo (Internist). 
Infographic by Dr. Valerie Kim (Internal Medicine Resident)    Support the Show.

233. Marrow’s Most Wanted- An Approach to Pancytopenia

In today's episode we take you through our approach to a disease with a wide array of clinical presentations and evolving treatment landscape - hypertrophic obstructive cardiomyopathy. 
Written by: Dr. Kate Haichin (Internal Medicine Resident) 
Reviewed by: Dr. Michael Chetrit (Cardiologist) & Dr. John Angelopoulos (General Internist)  Support the Show.

232. In the Thick of the Action - An Approach to Hypertrophic Obstructive Cardiomyopathy

Do you know you valvulopathies? Learn everything there is to know about mitral stenosis! This episode was written by Dr. David Ji (Internal Medicine Resident) and reviewed by Dr. Murray Kornbluth (Cardiology) and Dr. Samuel Mamane (General Internal Medicine). Infographic by Julie Simone (Medical Student).  Support the Show.

221. Red Pulp, White Pulp - An approach to splenomegaly

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