We go inside Northwestern Medicine’s Innovation Engine to see how they are solving healthcare’s biggest challenges with Kali Arduini Ihde, Director of Ventures and Innovation at Northwestern Medicine. Kali is at the forefront of bringing emerging technologies into one of the country’s top academic health systems to help shape the future of patient care through innovation. She leads the Northwestern Medicine Healthcare Accelerator, which partners with AI and digital health startups to solve real, high-impact challenges in healthcare. We discuss the value of creating organized programmatic innovation to solve important problems (prior authorization, physician burden, supply chain) in a safe space that allows for co-creation to accelerate scale.