Regression analysis explained — understanding how variables influence outcomes is essential for interpreting clinical research in this episode of This Is Why with Dr. Busti.

Dr. Busti breaks down regression analysis and how it helps identify relationships between variables while controlling for confounders. This Is Why mastering regression allows you to determine whether an intervention truly drives outcomes—or if other factors are influencing the results.

You’ll learn the difference between linear and multivariate regression, how independent and dependent variables interact, and why controlling for confounders is critical for internal validity. Dr. Busti also connects regression analysis to the bigger picture of evidence-based medicine, helping you integrate statistical tools into real clinical decision-making.

Topics Covered:
- What regression analysis actually measures
- Independent vs dependent variables
- Linear regression and line of best fit
- Multivariate (multilinear) regression explained
- Logistic regression and outcome prediction
- Identifying and controlling confounders
- Reasons variables may not show significance
- Role of sample size and statistical power
- Internal vs external validity connection
- Applying regression to clinical research interpretation

The goal = make medical education easy and clinically relevant.

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#regressionanalysis #confounders #biostatistics #clinicalresearch #Dr Busti

Speaker:
Anthony Busti, MD, PharmD, MSc, FAHA, FNLA, is a licensed healthcare professional and medical educator with over 30 years of experience in clinical practice and academic teaching. He has trained and practiced as a nurse, pharmacist, and physician, bringing a uniquely comprehensive perspective to patient care and medical education.
Dr. Busti is dedicated to advancing evidence-based medicine and helping clinicians understand the underlying “why” behind clinical decisions to improve patient outcomes.

About This Channel:
This content is created by Anthony Busti, MD, PharmD, MSc, FAHA, FNLA, a board-certified physician with training at Johns Hopkins School of Medicine and University of Oxford and a medical educator for healthcare professionals and students. All material is based on current medical literature and evidence-based guidelines that align with principles of evidence-based medicine (EBM) and Evidence-Based Healthcare (EBHC).

Disclaimer:
This content is for educational purposes only and is not medical advice. It does not replace individualized evaluation, diagnosis, or treatment. Always seek the advice of a qualified health provider with questions about a medical condition and never delay care because of educational content.