In this episode, JGME Editor-in-Chief, Dr. Gail Sullivan, speaks with 3 guests who were integral to the latest supplement issue Reimagining Residency: An American Medical Association Initiative to Transform GME. Starting in 2019, the AMA funded eleven 5-year grants with a goal to transform residency training to best address the workplace needs of our current and future health care system. This supplement issue is a collection of findings from the innovation projects that represent real-world applications of ideas that address pressing issues for trainees, program leaders, health care systems, and patients.