What causes our souls to be weary and heavy burdened? There can be physical, circumstantial, and spiritual causes. One of the main spiritual causes of misery is guilt. People will spend thousands of dollars and countles hours in therapy trying to get rid of the feeling of guilt. Even Christians can feel overwhelmed with feeling accused and condemned by God. We believe we have sinned too much and lost God's love. He is angry with us. We doubt that we have ever been a Christian. To relieve the burden of guilt we need to understand who we are in Christ: regenerated by God and reconciled to God. We are a new creation and have a new relationship through faith in Jesus.