Vidcast:  https://youtu.be/CmwdpRQqV_0

 

I’m attending the National Assn. of Broadcasters Meeting this week.  Here is some evergreen “Health News You Can Always Use.”

 

Exercise not only strengthens your heart, tones your muscles, and drives more blood flow to your brain, it also trains your fat cells to release healthy proteins into your blood that help keep your body humming.  New research from Harvard’s Joslin Diabetes Center just published in Nature Metabolism demonstrate that exercise-primed fat releases a healthy so-called adipokine that improves glucose metabolism.

 

This magic protein, Transforming Growth Factor Beta 2 or TGFbeta2, appears in both humans and mice as the result of exercise.  It controls blood sugar levels and neutralizes the effect of a high fat diet which in mice and in many humans induces diabetes.

 

Your muscles do play a role in the process too.  The lactic acid they produce as you exercise appears to be the trigger that leads to TGFbeta2 release from fat.  The investigators speculate that, someday, this key protein messenger released by fat may become a practical treatment for diabetes.

 

Takahashi et al. TGF-B2 is an Exercise-Induced Adipokine that Regulates Glucose and Fatty Acid Metabolism. Nature Metabolism, 2019 DOI: 10.1038/s42255-018-0030-7

 

#fat #adiposetissue #obesity #diabetes #TGFbeta2 #transforminggrowthfactor