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November 28, 2025

Results from the SOUL Trial: The Cardiologists' Perspective

8 minutes

Watch the full video on YouTube to explore the cardiologist’s perspective on one of the most important cardiovascular outcomes trials in recent years.

In this episode, Vivienne Parry speaks with Dr Matthew Cavender (University of North Carolina) about the SOUL trial, which evaluated the cardiovascular impact of oral semaglutide in more than 8,000 people with type 2 diabetes.

They discuss:

How oral semaglutide reduced major cardiovascular events by 14%

Why an oral GLP-1 receptor agonist may broaden access and adherence

Implications for diabetologist's, cardiologists and primary care

How team-based care can improve uptake of evidence-based therapies

What the latest ESC guidelines mean for future prescribing

🎧 Listen now for a clear, accessible breakdown of a landmark study reshaping diabetes and cardiovascular risk management. To learn more about our expert speaker:

Dr Matthew Cavender

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By EASD - European Association for the Study of Diabetes