What started as a story about Hollywood waistlines has become a global phenomenon. Weight loss drugs are becoming more and more mainstream a few years after making their dramatic debut. On this weekend episode of Reuters World News, our health reporters weigh in on the impact of these game-changing drugs, and where they go from here. 

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A Trump-endorsed spending bill has failed in the U.S. House leaving Congress with no clear path to dodge a government shutdown. Russian President Vladimir Putin says he is ready to compromise on Ukraine in possible talks with President-elect Donald Trump on ending the war. Target and Walmart are targeting cash-strapped holiday shoppers with $10 toys and gifts. And Hollywood is pivoting to God, the American West and outdoor enthusiasts to seize a wider audience. 

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Dominique Pelicot has been found guilty of all charges and sentenced to 20 years. The mass rape trial in France has transformed the victim, Gisele Pelicot, into a stirring symbol of courage and resilience. Donald Trump has disrupted bipartisan efforts to dodge a government shutdown, pressuring Republicans to reject a stopgap bill. The Fed’s rate cut lands as expected, but policymakers are starting to price in expectations of economic changes under the incoming administration. And Iran’s Revolutionary Guards have tightened their grip on

the country’s oil.

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Syrian mass graves expose “machinery of death” under toppled Bashar al-Assad, according to a top international war crimes prosecutor. Mayotte authorities fear hunger and disease after a devastating cyclone. President-elect Donald Trump sues the Des Moines Register newspaper and its former top pollster and threatens more news outlet lawsuits. And Tulsi Gabbard’s nomination to become the Director of National Intelligence might be on shaky ground as eight Republican senators are on the fence about supporting her.  

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Ukraine says it was behind the assassination of a top Russian general in a bomb blast in Moscow. The sudden resignation of Canada's finance minister has left Justin Trudeau’s government on the brink. An expanding coalition of health and consumer advocates is campaigning against Robert F. Kennedy Jr.'s nomination to the top U.S. health job. And President-elect Donald Trump has weighed into the mystery of increased drone sightings that have plagued the East Coast in the last few weeks.

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Listen to our special weekend episode with the Reuters journalist Suleiman al-Khadi, who was arrested by Syrian security police in 2011 here.

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Hundreds or even thousands are feared dead after a powerful cyclone slams into the French overseas territory of Mayotte. Israel wants to double its population on the ccupied Golan Heights, just over a week after the fall of the Assad regime in neighboring Syria. President-elect Donald Trump’s transition team is looking at cutting off federal support for electric vehicles. Plus, Canada’s promised border crackdown is easier said than done.

Find our recommended read about President Bashar al-Assad’s final hours in Syria here.

Our weekend episode was also on Syria and features the Reuters journalist Suleiman al-Khadi who was arrested by Syrian security police in 2011. Listen here.

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Reuters journalist Suleiman al-Khalidi was arrested by Syrian security police in 2011 during an uprising against President Bashar al-Assad. Hear what al-Khalidi witnessed back then and what it was like to see prisoners freed after Assad’s downfall.

You can read Suleiman's account of his detention from 2011 here.

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Time magazine names President-elect Donald Trump ‘Person of the Year’ - and his accompanying interview gives clues about his day one plans. Cargo planes from the UAE have been landing at a small airstrip in Chad that some U.N. experts suspect is being used to funnel arms across the border into Sudan. And the dilemma facing Ukrainian teenage boys ahead of their 18th birthdays.   

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FBI Director Christopher Wray will step down from his post after President-elect Donald Trump signaled his plan to fire him and replace him with Kash Patel. A crypto venture unveiled by Trump and his new Middle East envoy Steve Witkoff has partnered with a crypto platform that authorities and financial experts say has been used by criminals and militant groups. And Syrians in Europe consider whether to return home following the fall of Bashar al-Assad. 

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The Israeli military says its air strikes have destroyed the bulk of Syria’s strategic weapons stockpiles. Luigi Mangione, the suspect in the murder of UnitedHealth executive Brian Thompson, plans to fight extradition to New York. And we look at TikTok’s future after a federal appeals court upholds a U.S. law requiring Chinese-owned ByteDance to spin off the social media app. 

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