This podcast episode discusses the concept of neuroplasticity, the brain's ability to change and adapt throughout life. the guys discuss neuroplasticity, including the strengthening or weakening of neural connections, the growth of new neurons, and structural changes in the brain. They talk about how to leverage neuroplasticity to improve one's life by engaging in activities like learning new skills, practicing mindfulness, and engaging in physical activity. Finally, the episode explores the clinical applications of neuroplasticity, such as stroke rehabilitation and the treatment of chronic pain, while acknowledging its limitations and emphasizing the importance of creating positive and enriching environments for healthy brain development.