Rhabdomyolysis, the destruction of muscle tissue, leading to risk of systemic complications, can be caused from a number of traumatic and non-traumatic mechanisms. Rhabdomyolysis is a confusing pathology to understand, and involves a fairly deep knowledge level of how the muscle cell works. In this episode of Back to Basics, the Seitz brothers simplify the understanding of how muscle cells work and how to both suspect and treat rhabdomyolysis in the acute emergency setting!