In this episode of RhAPPcast, the official podcast of Rheumatology Advanced Practice Providers, host Amanda Mixon, PA-C, is joined by Heather Finlayson, PA-C, to discuss treat-to-target strategies in lupus management and how DORIS remission can be applied in real-world clinical practice. This conversation explores what successful lupus care looks like beyond flare management, including steroid minimization, low disease activity, shared decision-making, and the use of objective tools such as SLEDAI-2K to monitor disease activity. Listeners will gain practical insights on setting realistic remission goals, reducing long-term prednisone burden, recognizing when to escalate therapy, and helping patients understand that remission in systemic lupus erythematosus means stable disease control on therapy. Designed for rheumatology APPs and clinicians, this episode offers actionable strategies to improve lupus outcomes, support patient-centered care, and bring treat-to-target goals into everyday practice.