Rheumatoid arthritis: Pathophysiology, clinical features, investigations and management.

Memory pegs used:

Risk factors: SHO AF

Extra articular manifestations: PB & J FC, ALE

Ocular manifestation: DRS CUE

In this medical education episode, we dive into rheumatoid arthritis, a chronic autoimmune condition characterized by inflammation of the synovium due to anti-CCP antibodies. We'll explore the key risk factors, including family history, smoking, obesity, and age, as well as the common clinical features—systemic and articular symptoms. Learn about essential investigations such as serology, imaging, and ultrasound, and discover effective management strategies, including lifestyle changes, DMARDs, biological DMARDs, steroids, and NSAIDs. We’ll also discuss important medication side effects and contraindications.