Sign up to save your podcasts
Or
Share Riesgo de Trombosis e Inhibidores de JAK
Share to email
Share to Facebook
Share to X
Share to email
Share to Facebook
Share to X
Or
Riesgo de Trombosis e Inhibidores de JAK
Han sido muchos meses desde que nos escuchamos la última vez. En este episodio, hablaré de la evidencia que hay sobre riesgo de tromboembolismo venoso en pacientes que usan inhibidores de JAK.
Estas son algunas referencias revisadas para este episodio.
Les agradezco su continuado apoyo y su paciencia. Por favor difundan este podcast entre sus conocidos.
Choi, H. K. et al. The risk of pulmonary embolism and deep vein thrombosis in rheumatoid arthritis: a UK population-based outpatient cohort study. Ann. Rheum. Dis. 72, 1182–1187 (2013).
Cohen, S. B. et al. Safety profile of upadacitinib in rheumatoid arthritis: integrated analysis from the SELECT phase III clinical programme. Ann. Rheum. Dis. https://doi.org/10.1136/annrheumdis-2020-218510 (2020).
Genovese, M. et al. Safety profile of baricitinib for the treatment of rheumatoid arthritis over a median of 3 years of treatment: an updated integrated safety analysis. Lancet Rheumatol. 2, E347–E357 (2020).
Mease, P. et al. Incidence of venous and arterial thromboembolic events reported in the tofacitinib rheumatoid arthritis, psoriasis and psoriatic arthritis development programmes and from real-world data. Ann. Rheum. Dis. 79, 1400–1413 (2020).
Molander, V., Bower, H. & Askling, J. Does the risk of venous thromboembolism vary with disease activity in rheumatoid arthritis? [abstract]. Ann. Rheum. Dis. 79 (Suppl. 1), 23–24 (2020).
Sandborn, W. J. et al. Venous thromboembolic events in the tofacitinib ulcerative colitis clinical development programme. Aliment. Pharmacol. Ther. 50, 1068–1076 (2019).
Samuelson, B. T. et al. The impact of ruxolitinib on thrombosis in patients with polycythemia vera and myelofibrosis: a meta-analysis. Blood Coagul. Fibrinolysis 27, 648–652 (2016).
Yates, M. et al. Venous thromboembolism risk with JAK inhibitors: a meta-analysis. Arthritis Rheumatol. https://doi.org/10.1002/art.41580 (2020).
Winthrop, K. L. The emerging safety profile of JAK inhibitors in rheumatic disease. Nat. Rev. Rheumatol. 13, 234–243 (2017).
Winthrop, K. et al. Integrated safety of filgotinib in patients with moderately or severely active rheumatoid arthritis receiving treatment for up to 5.5 years [abstract]. Arthritis Rheumatol. 72 (Suppl. 10), 229 (2020).
View all episodes
By Daniel Xibille FriedmannHan sido muchos meses desde que nos escuchamos la última vez. En este episodio, hablaré de la evidencia que hay sobre riesgo de tromboembolismo venoso en pacientes que usan inhibidores de JAK.
Estas son algunas referencias revisadas para este episodio.
Les agradezco su continuado apoyo y su paciencia. Por favor difundan este podcast entre sus conocidos.
Choi, H. K. et al. The risk of pulmonary embolism and deep vein thrombosis in rheumatoid arthritis: a UK population-based outpatient cohort study. Ann. Rheum. Dis. 72, 1182–1187 (2013).
Cohen, S. B. et al. Safety profile of upadacitinib in rheumatoid arthritis: integrated analysis from the SELECT phase III clinical programme. Ann. Rheum. Dis. https://doi.org/10.1136/annrheumdis-2020-218510 (2020).
Genovese, M. et al. Safety profile of baricitinib for the treatment of rheumatoid arthritis over a median of 3 years of treatment: an updated integrated safety analysis. Lancet Rheumatol. 2, E347–E357 (2020).
Mease, P. et al. Incidence of venous and arterial thromboembolic events reported in the tofacitinib rheumatoid arthritis, psoriasis and psoriatic arthritis development programmes and from real-world data. Ann. Rheum. Dis. 79, 1400–1413 (2020).
Molander, V., Bower, H. & Askling, J. Does the risk of venous thromboembolism vary with disease activity in rheumatoid arthritis? [abstract]. Ann. Rheum. Dis. 79 (Suppl. 1), 23–24 (2020).
Sandborn, W. J. et al. Venous thromboembolic events in the tofacitinib ulcerative colitis clinical development programme. Aliment. Pharmacol. Ther. 50, 1068–1076 (2019).
Samuelson, B. T. et al. The impact of ruxolitinib on thrombosis in patients with polycythemia vera and myelofibrosis: a meta-analysis. Blood Coagul. Fibrinolysis 27, 648–652 (2016).
Yates, M. et al. Venous thromboembolism risk with JAK inhibitors: a meta-analysis. Arthritis Rheumatol. https://doi.org/10.1002/art.41580 (2020).
Winthrop, K. L. The emerging safety profile of JAK inhibitors in rheumatic disease. Nat. Rev. Rheumatol. 13, 234–243 (2017).
Winthrop, K. et al. Integrated safety of filgotinib in patients with moderately or severely active rheumatoid arthritis receiving treatment for up to 5.5 years [abstract]. Arthritis Rheumatol. 72 (Suppl. 10), 229 (2020).