The sermon centers on Romans 10:14–17, emphasizing that faith arises from hearing the gospel, which requires preaching, and preaching demands being sent by God—highlighting the necessity of both evangelistic proclamation and divine commission. It distinguishes between the general call to all people and the efficacious call that results in salvation, affirming that while preaching is the normal means by which God saves, He remains sovereign over all, including those who have never heard the gospel. The passage underscores that salvation is not earned by human effort or knowledge but is entirely God's work, with the preacher's role being one of divine appointment, not self-appointment. The sermon also addresses the pastoral and theological challenge of those who have never heard the gospel, affirming that God's justice and mercy are beyond human comprehension, and that the church's duty is to faithfully proclaim the gospel as the ordained means, trusting in God's sovereign grace to save His elect in ways known only to Him.