It is not often we have a major paradigm shift in medicine.

Albert Broders, MD, was a pathologist at the Mayo Clinic. Early in his career, he described tumor grading, showing for the first time that features in cancer specimens observed under the microscope could predict outcomes.

This discovery was a massive paradigm shift, that quickly begat tumor staging and eventually the whole predictive biomarker field.

Rondell Graham, Head of GI and Liver Pathology at the Mayo Clinic, joins us this week on The Personalized Diagnostics Podcast, where we discuss predictive and prognostic markers in colon cancer, molecular diagnostics, digital pathology, the future of targeted therapies and much more.