Dr. Alexis "AC" Gomez, a second year fellow in the combined MGH, Brigham and Women's, and Boston Children's nephrology fellowship, continues a discussion of sodium disorders with a conversation about hypernatremia with Dr. Joyce Zhou, a RTL host and internal medicine resident. She shares her approach to high sodium disorders and pearls on diagnostics and management of this disorder.

Dr. Alexis "AC" Gomez, a second year fellow at the combined MGH, Brigham and Women's, and Boston Children's nephrology program, discusses her approach to hyponatremia with host Dr. Joyce Zhou. She shares the pathophysiology behind her diagnostic framework for hyponatremia and her systematic approach, and discusses pearls such as how to use ddAVP clamps in treating this disorder.

Dr. Samira Farouk, transplant nephrologist at the Mount Sinai Hospital in New York, continues our nephrology series with a discussion of hypokalemia. She and Dr. Emily Gutowski, RTL host, cover the potential causes of low potassium and important concepts to keep in mind while treating this electrolyte disturbance.

Dr. Rahul Maheshwari, second year nephrology fellow at the Mount Sinai Hospital in New York, discusses hyperkalemia with Dr. Emily Gutowski, a RTL host and internal medicine resident. They cover the potential causes of elevated potassium, how to think about acuity, and treatment guidelines to correct this electrolyte disturbance.

Dr. Rahul Maheshwari, second year nephrology fellow at the Mount Sinai Hospital in New York, discusses acute kidney injury with Dr. Emily Gutowski, a RTL host and internal medicine resident. Together, they discuss the presentation, differential diagnosis, and treatment considerations of AKI.

Dr. Raymond Chung, a gastroenterologist and Transplant Hematologist who is the Director of the Hepatology and Liver Center at MGH and a Professor of Medicine at Harvard Medical School, discusses acute liver failure with Dr. Joyce Zhou, a RTL host and internal medicine resident. In the episode, he defines acute liver failure (ALF) and discusses pathophysiology, etiologies of ALF, complications by system, and tenets of management. He also discusses new treatments for liver failure in the developmental pipeline.

Dr. Raymond Chung, a Gastroenterologist and Transplant Hepatologist who is the Director of the Hepatology and Liver Center at MGH and a Professor of Medicine at Harvard Medical School, joins host of RTL and internal medicine resident, Dr. Joyce Zhou, to discuss an approach to decompensated cirrhosis. In the episode, the two cover underlying pathophysiology, complications, and management of patients with cirrhosis from oral medications through transplant consideration. Their discussion touches on ascites, esophageal varices, hepatic encephalopathy, SBP diagnosis, TIPS use, hepato-renal syndrome, and more. The episode closes with Dr. Chung’s big picture pearls for thinking about and caring for cirrhotic patients.

Dr. Sasha-Deutsch Link, a Gastroenterology and Hepatology fellow at the University of North Carolina (UNC), joins host her co-fellow Dr. Walker Redd, co-founder and host of RTL, to discuss Alcohol-Associated Liver Disease. Through a case discussion of a patient with acute alcohol-associated hepatitis, they review patient-centered terminology, the relevant diagnostic workup, and how to think both acute and chronic alcohol-associated liver disease. They also cover important principles of management, including supportive care, nutrition, pyschosocial support, pharmacotherapy for alcohol cessation, and consideration of early liver transplant, as well as the importance of longitudinal follow-up.

Dr. Navin Kumar, an attending Gastroenterologist at Brigham and Women's Hospital, medical educator at Harvard Medical School, and co-founder of the Run the List podcast and host Blake Smith discuss how to approach a patient presenting with acute right-upper quadrant (RUQ) pain. Together, they discuss the various causes of RUQ pain, in addition to how to approach a set of liver function tests (LFTs), differentiating hepatocellular injury from a cholestatic pattern. They then discuss how various forms of imaging (RUQUS, CT) can guide diagnosis and management, leading to a discussion about the use of ERCP and cholecystectomy in such cases. Lastly, the episode closes with a diagnosis and three clinical pearls about RUQ pain and abnormal LFTs.

Dr. Navin Kumar, an attending gastroenterologist at Brigham and Women's Hospital, medical educator at Harvard Medical School, and co-founder of the Run the List podcast and Dr. Walker Redd, a Gastroenterology fellow at the University of North Carolina and co-founder of RTL, discuss Inflammatory Bowel Disease. Building on the prior episode covering an approach to diarrhea, they first discuss diagnosing IBD and distinguishing between ulcerative colitis (UC) and Crohn's disease (CD). Through a case discussion of a patient with UC, they provide an overview the initial management options for lower risk patients with mild to moderate UC and then review how to manage an acute, severe UC flare.