What if extinction is not forever? Recent advances in ancient DNA research and genome engineering technologies have opened the door to turning this idea from science fiction into science fact. But, how close are we to actually making de-extinction happen, and, are there compelling reasons to do so? In this talk, ancient DNA scientist Beth Shapiro discussed the science and ethics of de-extinction, including what is and what is not technically possible today and how scientists might overcome the existing barriers to bringing extinct species back to life.