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In the inverted language of MBC, “unremarkable” is something we all aspire to, and “progression” is something we dread. Progression means that our current medication regimen is no longer working and cancer is spreading and/or growing. It means that treatment is likely to change—bringing new drugs with new side effects. It also means that we’ve exhausted one of the available treatment options for our disease, leaving fewer remaining lines of treatment. In this episode, breast oncologist Dr. Stephanie L. Graff helps us unravel the mysteries of progression and resistance, tissue and liquid biopsies, tumor markers and scans. 
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