The coagulation cascade isn’t just a lecture topic—it’s a life-or-death system unfolding in real time in trauma bays, ORs, and ICUs. What happens when the cascade misfires? In this episode, we explore not just the science, but the stories, of three patients whose bleeding or clotting disorders reveal the power and peril of the clotting cascade. From a child with hemarthrosis to a septic patient in DIC, you’ll see how lab values like INR and aPTT are more than just numbers—they're clinical lifelines.