Drs Madhukar Trivedi and Anita Clayton discuss how to approach patients with sexual dysfunction who are being treated for major depressive disorder.

Relevant disclosures can be found with the episode show notes on Medscape (https://www.medscape.com/viewarticle/984459). The topics and discussions are planned, produced, and reviewed independently of advertisers. This podcast is intended only for US healthcare professionals.

Resources

Depression https://emedicine.medscape.com/article/286759-overview

Treatment-Emergent Sexual Dysfunction Related to Antidepressants: A Meta-Analysis https://pubmed.ncbi.nlm.nih.gov/19440080/

Citizen Petition: Sexual Side Effects of SSRIs and SNRIs https://pubmed.ncbi.nlm.nih.gov/29733031/

Association of Major Depression With Sexual Dysfunction in Men https://pubmed.ncbi.nlm.nih.gov/23645187/

The Changes in Sexual Functioning Questionnaire (CSFQ): Development, Reliability, and Validity https://pubmed.ncbi.nlm.nih.gov/9493486/

Structured Review of the Use of the Arizona Sexual Experiences Scale in Clinical Settings https://pubmed.ncbi.nlm.nih.gov/32236977/

Hypoactive Sexual Desire Disorder: A Review of Epidemiology, Biopsychology, Diagnosis, and Treatment https://pubmed.ncbi.nlm.nih.gov/27872021/

Erectile Dysfunction https://pubmed.ncbi.nlm.nih.gov/31030826/

Sexual Dysfunction With Major Depressive Disorder and Antidepressant Treatments: Impact, Assessment, and Management https://pubmed.ncbi.nlm.nih.gov/35255754/

Overview of the Rapid Antidepressant Effects Observed in the Zuranolone Clinical Development Program https://journals.lww.com/greenjournal/Abstract/2022/05001/Overview_of_the_Rapid_Antidepressant_Effects.161.aspx

Flibanserin prescribing information https://www.accessdata.fda.gov/drugsatfda_docs/label/2015/022526lbl.pdf