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How do our bodies remember a virus they haven't seen in a decade? What exactly makes the "adaptive" part of our immune system so much more specialized than our innate defenses? This and much more in this new episode of The Viral Talk.
Key takeaways:
- The adaptive immune response kicks in later compared to the innate immune response.
- Its main actors are B and T cells.
- B cells produce antibodies against the pathogens.
- Antibodies are small proteins that target very specific bits on the surface of pathogens called antigens.
- Antigens are like the fingerprints of the pathogens. Each virus/bug/yeast has unique antigens, which are only recognised by some antibodies.
- T cells divide into three types of cells: T-regs, T-killer and T-memory cells.
- Killer T cells (Cytotoxic T cells) are the front-line soldiers that identify and destroy your own cells that have been hijacked by viruses or have become cancerous.
- Memory T cells serve as a long-term surveillance team, "remembering" the specific signature of a pathogen so the body can launch a near-instant and more powerful defense if that same invader ever returns.
- Helper T cells sense threats and release chemical signals called cytokines to coordinate the entire immune response, including the activation of B cells.
- Antibodies are generated fresh after each infection via multiple rounds genetic recombination within B cells.
For the sciency folk:
A short review on the adaptive immune response - https://www.ncbi.nlm.nih.gov/books/NBK21070/
Adaptive immunity for dummies - https://www.dummies.com/article/academics-the-arts/science/biology/adaptive-immunity-168885/
Review article on adaptive immunity and vaccinology - https://www.nature.com/articles/s41577-020-00479-7
Timestamps:
Core episode start - 1.48
News of the day - 18.27
Viral question - 39.00
Call to actions:
Follow us on Spotify - https://open.spotify.com/show/6dLMIpVOO1F0rn8REUbymv?si=94900fda0c884465
Follow us on IG - https://www.instagram.com/the_viral_talk_/
Follow us on X - https://x.com/The_Viral_Talk
Leave a review on Podchaser.com - https://www.podchaser.com/podcasts/the-viral-talk-5094049
By Federico De Angelis, Bobbie-Anne TurnerHow do our bodies remember a virus they haven't seen in a decade? What exactly makes the "adaptive" part of our immune system so much more specialized than our innate defenses? This and much more in this new episode of The Viral Talk.
Key takeaways:
- The adaptive immune response kicks in later compared to the innate immune response.
- Its main actors are B and T cells.
- B cells produce antibodies against the pathogens.
- Antibodies are small proteins that target very specific bits on the surface of pathogens called antigens.
- Antigens are like the fingerprints of the pathogens. Each virus/bug/yeast has unique antigens, which are only recognised by some antibodies.
- T cells divide into three types of cells: T-regs, T-killer and T-memory cells.
- Killer T cells (Cytotoxic T cells) are the front-line soldiers that identify and destroy your own cells that have been hijacked by viruses or have become cancerous.
- Memory T cells serve as a long-term surveillance team, "remembering" the specific signature of a pathogen so the body can launch a near-instant and more powerful defense if that same invader ever returns.
- Helper T cells sense threats and release chemical signals called cytokines to coordinate the entire immune response, including the activation of B cells.
- Antibodies are generated fresh after each infection via multiple rounds genetic recombination within B cells.
For the sciency folk:
A short review on the adaptive immune response - https://www.ncbi.nlm.nih.gov/books/NBK21070/
Adaptive immunity for dummies - https://www.dummies.com/article/academics-the-arts/science/biology/adaptive-immunity-168885/
Review article on adaptive immunity and vaccinology - https://www.nature.com/articles/s41577-020-00479-7
Timestamps:
Core episode start - 1.48
News of the day - 18.27
Viral question - 39.00
Call to actions:
Follow us on Spotify - https://open.spotify.com/show/6dLMIpVOO1F0rn8REUbymv?si=94900fda0c884465
Follow us on IG - https://www.instagram.com/the_viral_talk_/
Follow us on X - https://x.com/The_Viral_Talk
Leave a review on Podchaser.com - https://www.podchaser.com/podcasts/the-viral-talk-5094049