Dr Jeffrey Swigris and Janet Talbert discuss the current understanding of the genetics of pulmonary fibrosis, explore the identified genetic pathways, and discuss future research directions.

Relevant disclosures can be found with the episode show notes on Medscape https://www.medscape.com/viewarticle/999863. The topics and discussions are planned, produced, and reviewed independently of advertisers. This podcast is intended only for US healthcare professionals.

Resources

Pulmonary Fibrosis Predisposition Overview https://pubmed.ncbi.nlm.nih.gov/20301408/

Aging and Pulmonary Fibrosis https://pubmed.ncbi.nlm.nih.gov/27103043/

Telomere Length and Risk of Idiopathic Pulmonary Fibrosis and Chronic Obstructive Pulmonary Disease: A Mendelian Randomisation Study https://pubmed.ncbi.nlm.nih.gov/33197388/

Lung Fibrosis, Premature Graying, and Macrocytosis https://pubmed.ncbi.nlm.nih.gov/22942352/

Idiopathic Pulmonary Fibrosis Is Associated With Common Genetic Variants and Limited Rare Variants https://pubmed.ncbi.nlm.nih.gov/36602845/

Idiopathic Pulmonary Fibrosis and the Role of Genetics in the Era of Precision Medicine https://pubmed.ncbi.nlm.nih.gov/37181377/

Telomeres in Interstitial Lung Disease: The Short and the Long of It https://pubmed.ncbi.nlm.nih.gov/30540921/

Perceptions of Genetic Testing: A Mixed-Methods Study of Patients With Pulmonary Fibrosis and Their First-Degree Relatives https://pubmed.ncbi.nlm.nih.gov/35584322/

American College of Medical Genetics and Genomics https://www.acmg.net/

National Society of Genetic Counselors https://www.nsgc.org/

American Board of Genetic Counselors https://www.abgc.net/